The number of strains in a probiotic is rarely sufficient on its own. What matters more is which strains are selected, in what proportion, and how they interact with each other.
Onbiome Balance contains 9 biocompatible strains at a total concentration of no less than 200 billion CFU per capsule, with inulin as a prebiotic and an acid-resistant capsule designed to help deliver the live microorganisms to the intestines.
Important note: the properties and mechanisms described below are based on scientific publications for the respective microorganisms and strains. They do not represent a claim that each of these effects has been clinically proven for the Onbiome Balance product itself. This article is for educational purposes and does not constitute medical advice.
Strain by Strain
Lactobacillus rhamnosus - 51 billion CFU
The lead strain in the formula. Scientific studies describe its interaction with the immune system, including its influence on macrophages, secretory IgA, and immune response regulation. L. rhamnosus is among the most studied probiotic microorganisms.
Lactobacillus reuteri - 47 billion CFU
Associated with the production of antimicrobial substances, maintenance of the intestinal barrier, and regulation of the immune response. In certain strains and specific clinical conditions, effects have been observed in diarrhoea, constipation, and as a complementary approach in H. pylori infection.
Streptococcus thermophilus - 44 billion CFU
Actively participates in milk fermentation and contributes to enzyme production, including lactase. In the fermentation system it interacts with L. bulgaricus and contributes to the characteristic metabolic profile of yoghurt.
Lactobacillus casei - 32 billion CFU
Scientific literature examines the role of L. casei in intestinal function and its interaction with the gut microbiota. It produces lactic acid, which creates an environment unfavourable to a range of unwanted microorganisms.
Bifidobacterium infantis - 32 billion CFU
Associated with maintaining the intestinal mucosa and gut barrier function, as well as regulating the immune response. Research examines its interaction with epithelial cells and the immune system.
Bifidobacterium longum - 32 billion CFU
Studied in relation to the regulation of inflammatory processes and its interaction with the intestinal environment. It participates in microbial metabolism and the formation of various metabolites, including short-chain fatty acids.
Lactobacillus plantarum - 27 billion CFU
Scientific studies associate L. plantarum with maintaining the intestinal barrier and modulating inflammatory signalling pathways. In the formula it functionally complements B. longum and B. infantis.
Lactobacillus acidophilus - 5 billion CFU
Produces organic acids and other antimicrobial metabolites that can limit the growth of certain unwanted microorganisms. In the formula it plays a complementary role to the higher-concentration strains.
Lactobacillus bulgaricus - 1 billion CFU
A characteristic microorganism of traditional Bulgarian dairy fermentation. It is a transit microorganism in the human digestive tract, but plays an important technological and metabolic role in fermentation and interacts with S. thermophilus.
Why the Proportion Matters
Within the formula we can broadly distinguish three functional levels:
Immune Regulation
L. rhamnosus and L. reuteri - 98 billion CFU
These two strains form the primary group in the formula associated with the interaction between the microbiota and the immune system.
Intestinal Barrier
B. infantis, B. longum and L. plantarum - 91 billion CFU
These microorganisms have been studied in relation to the intestinal barrier, interaction with the intestinal epithelium, and regulation of inflammatory processes.
Environmental Preparation
S. thermophilus, L. casei, L. acidophilus and L. bulgaricus - 94 billion CFU
This group complements the formula through various metabolic and fermentation functions.
Inulin acts as a prebiotic substrate that can support the growth and metabolic activity of bifidobacteria. Part of microbial metabolism involves the formation of short-chain fatty acids, which play an important role in communication between the microbiota and the body.
The Proportion Is Not Accidental
At the time of production, the formula contains a total of 271 billion CFU distributed among the nine strains. However, this is not the number that should be regarded as a guarantee for the consumer.
The viability of microorganisms naturally changes during storage. That is why Onbiome Balance guarantees no less than 200 billion CFU until the end of the expiry date. This means that even when taken on the last possible day before expiry, the consumer receives the guaranteed quantity of viable microorganisms.
The Balance formula has been created with a specific biological and technological logic - the lead strains are present in higher concentrations, the next complement the functional profile, and the remaining participate in building the overall microbial combination. That is precisely why, with a synbiotic, it is not enough to count the strains. What matters is their selection, quantity, compatibility, and their place within the overall formula.
Read More
Postbiotics - The Third Level of Fermentation Science That the World Is Only Beginning to Discover
What Is a Synbiotic and Why Is It Better Than a Regular Probiotic?
This article is for educational purposes and does not replace medical consultation.
